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FREE SHIPPING for Prime members. Xenical (orlistat) is a prescription weight-loss medication. Learn about Xenical, generic orlistat, and over-the-counter Alli costs, insurance coverage, and savings. Xenical is a meal time pill that reduces fat intake by up to 33%. Xenical contains the active ingredient orlistat. Consult a clinician today. Buy online with fast US delivery. Compare Xenical (orlistat) prices from accredited international online pharmacies, U.S. mail-order pharmacies, and discount coupon programs. The lowest available price for Xenical (orlistat) 120 mg is $0.63 per capsule for 168 capsules at PharmacyChecker-accredited online pharmacies. You save 87% off the average U.S. pharmacy retail price of $5.04 per capsule for 90 capsules. 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