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Do not split your dose throughout the … Adcirca (Tadalafil) Adcirca (Tadalafil) is a prescription medication for treating pulmonary arterial hypertension (PAH). It works by relaxing blood vessels in the lungs, improving blood flow, and reducing the workload on the heart. Why Choose Adcirca (Tadalafil)? Improves blood flow: Enhances oxygen delivery by widening lung blood vessels. Boosts exercise capacity: Helps you stay active by … Before taking tadalafil, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. How ADCIRCA® (tadalafil) may help you ADCIRCA was shown to improve exercise ability in patients with PAH in a large 16-week clinical study. Patients taking ADCIRCA: Increased their 6-minute walk distance (6MWD) after 16 weeks of treatment by an average of 33 meters, or 108 feet compared to patients taking a placebo (sugar pill). 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